Saturday, January 7, 2023

Symbicort Budesonide and Formoterol Fumarate Dihydrate: Uses, Dosage, Side Effects, Interactions, Warning

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Sharing this information can help you avoid potential interactions. For instance, some interactions can interfere with how well a drug works. Other interactions can increase the number of side effects or make them more severe.

Never immerse the canister into water to determine the amount remaining in the canister (“float test”). SYMBICORT is indicated for the treatment of asthma in patients 6 years of age and older. Formoterol fumarate dihydrate is a powder which is slightly soluble in water. The pKa of formoterol fumarate dihydrate at 25°C is 7.9 for the phenolic group and 9.2 for the amino group. Montelukast oral tablet is a generic prescription drug used to treat asthma and allergies. If you have ketoacidosis or diabetes, taking Symbicort may make your condition worse.

They’ll help you decide on the best way to feed your child and what asthma and chronic obstructive pulmonary disorder treatment options are right for you. If you’re currently pregnant or thinking about becoming pregnant, talk with your doctor. They can recommend the best asthma and chronic obstructive pulmonary disorder treatment options for you. Symbicort comes as a metered-dose inhaler, which dispenses the drug in a spray that you inhale. You’ll take two puffs of Symbicort twice a day for the treatment of asthma or COPD.

As with other products containing beta2-agonists, special caution should be observed when using SYMBICORT in geriatric patients who have concomitant cardiovascular disease that could be adversely affected by beta2-agonists. Long-term studies were conducted in rats and mice using oral administration to evaluate the carcinogenic potential of budesonide. As with other inhaled medications, SYMBICORT can produce paradoxical bronchospasm, which may be life threatening.

Ask your doctor what other treatment options are better choices for you. Your insurance plan may require you to get prior authorization before they approve coverage for Symbicort. This means that your doctor will need to send a request to your insurance company asking them to cover the drug. The insurance company will review the request and let you and your doctor know if your plan will cover Symbicort. If you no longer need to take Symbicort and have leftover medication, it’s important to dispose of it safely.

Due to lack of specific data with the oral or rectal formulations, some manufacturers recommend therapy be avoided. Patients who are on drugs that suppress the immune systemare more susceptible to infection than healthy individuals. Chicken pox andmeasles, for example, can have a more serious or even fatal course in susceptible children or adults using corticosteroids. In such children or adults who have not had these diseases or been properly immunized, particular care should be taken to avoid exposure. How the dose, route, and duration of corticosteroid administration affects the risk of developing a disseminated infection is not known. The contribution of the underlying disease and/or prior corticosteroid treatment to the risk is also not known.

No teratogenic effects were observed at doses up to 3800 times the MRHDID (on a mcg/m² basis at maternal oral doses up to 3500 mcg/kg/day). Glaucoma, increased intraocular pressure, and cataracts have been reported in patients with asthma and COPD following the long-term administration of inhaled corticosteroids, including budesonide, a component of SYMBICORT. Therefore, close monitoring is warranted in patients with a change in vision or with history of increased intraocular pressure, glaucoma, and/or cataracts. Patients requiring oral corticosteroids should be weaned slowly from systemic corticosteroid use after transferring to SYMBICORT. Prednisone reduction can be accomplished by reducing the daily prednisone dose by 2.5 mg on a weekly basis during therapy with SYMBICORT.

FEV1 is the amount of air that you can force out of your lungs in 1 second. Changes in FEV1 were about the same between Symbicort and Breo, which showed that the drugs were similarly effective in easing people’s asthma symptoms. Breo comes as a dry powder inhaler, which dispenses the drug as a fine powder that you inhale. You’ll take one puff of Breo once a day for the treatment of asthma or COPD. While taking Symbicort, it’s important to tell your doctor right away if you notice dizziness, headaches, or heart palpitations .

SYMBICORT and certain other medicines may interact with each other. Especially tell your healthcare provider if you take antifungal or anti-HIV medicines. It is not known if SYMBICORT is safe and effective in children less than 6 years of age with asthma. Efficacy results for other secondary end points, including quality of life, were similar to those observed in Study 1. The percentage of patients withdrawing due to or meeting predefined criteria for worsening asthma is shown in Table 6.

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